Michel Abood
Michel Abood
OMG! That's awesome!
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An introduction and Paris Recommendation request
- Thread starter Kevin Roberts
- Start date
OMG! That's awesome!
I still remember how disappointed I was when I read Mullis' first PCR paper at the time of publication. I was working at the time on ways of amplifying a signal from DNA hybridization, and PCR seemed like the sort of thing that one could have conceived oneself, had one been just a tiny bit more on the ball. It was a forehead smacking moment.originally posted by VLM:
Small world, I just recently learned about PCR as well!!
And it turned out that it had been well described in an old Khorana paper, but never really reduced to practice or followed up.
OTOH, the inventor has turned into one of our more amusing Nobel laureates.
originally posted by SFJoe:
I still remember how disappointed I was when I read Mullis' first PCR paper at the time of publication. I was working at the time on ways of amplifying a signal from DNA hybridization, and PCR seemed like the sort of thing that one could have conceived oneself, had one been just a tiny bit more on the ball. It was a forehead smacking moment.originally posted by VLM:
Small world, I just recently learned about PCR as well!!
And it turned out that it had been well described in an old Khorana paper, but never really reduced to practice or followed up.
OTOH, the inventor has turned into one of our more amusing Nobel laureates.
Don't you love those moments? Pick up a new issue of (insert tier 1 journal here) and read the lead article, and well, duh. This is why I'm a pretty shitty academic.
Can you explain the amusing Nobel laureates comment? That went right past me.
A tame account from his wiki:originally posted by VLM: Can you explain the amusing Nobel laureates comment? That went right past me.
Mullis's 1998 autobiography Dancing Naked in the Mind Field, gives his account of the commercial development of PCR, as well as providing insights into the opinions and experiences of the author. In the book, Mullis chronicles his romantic relationships, use of LSD, synthesis and self-testing of novel psychoactive substances, belief in astrology and an encounter with an extraterrestrial in the form of a fluorescent raccoon.
He's pretty famous for taking LSD and surfing.
Oh, not always. I often meet people, Nobel laureates and such, and think, "dang, he's way smarter than I am and I never could have come up with that." Other times, they're mere mortals who had a good idea or picked the right problem. The latter group used to give me hope. But now that I'm a banker the standards are lower.originally posted by VLM:
Don't you love those moments? Pick up a new issue of (insert tier 1 journal here) and read the lead article, and well, duh. This is why I'm a pretty shitty academic.
Ruben Ramos
Ruben Ramos
What's PCR?
originally posted by SFJoe:
Oh, not always. I often meet people, Nobel laureates and such, and think, "dang, he's way smarter than I am and I never could have come up with that."originally posted by VLM:
Don't you love those moments? Pick up a new issue of (insert tier 1 journal here) and read the lead article, and well, duh. This is why I'm a pretty shitty academic.
Oh, make no mistake. That happens to me all the time.
Kevin Roberts
Kevin Roberts
originally posted by SFJoe:
Oh, not always. I often meet people, Nobel laureates and such, and think, "dang, he's way smarter than I am and I never could have come up with that." Other times, they're mere mortals who had a good idea or picked the right problem. The latter group used to give me hope. But now that I'm a banker the standards are lower.originally posted by VLM:
Don't you love those moments? Pick up a new issue of (insert tier 1 journal here) and read the lead article, and well, duh. This is why I'm a pretty shitty academic.
I feel the same way, discoveries are either "Wow, it seems so obvious and simple" or "Jesus, how does someone even think of that, let alone prove it."
about biology/immunology journals. I'm trying to replicate an analysis but there is not enough information in the paper nor the online supplement to do so. Pages and pages about staining this and titer that, blah, blah, blah. Don' these people realize the data is the science, not their little lab stuff, as cute as it is. More robust statistical analysis sections I say. Or at least give me a citation.
Hello,
Bad feeling about La Crmerie with a nervous boss (bad business in T4 ?), in a not very nice area (too many tourists...).
Nice food (top pork meat, lardo di colonnata...) at Racines (the ex-owner of La Crmerie) with very natural wines (a very hum-hum wine "Le champignon magique")
Best regards
pierre-alain benoit
www.tgjp.com
Bad feeling about La Crmerie with a nervous boss (bad business in T4 ?), in a not very nice area (too many tourists...).
Nice food (top pork meat, lardo di colonnata...) at Racines (the ex-owner of La Crmerie) with very natural wines (a very hum-hum wine "Le champignon magique")
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www.linternaute.com
pierre-alain benoit
www.tgjp.com
originally posted by Kevin Roberts:
I work for Integrated DNA, we sell DNA to the medical research market.
Funny, one of my first graduate students went to work there after getting his Ph. D. (in Organic Chemistry no less) with me. (He left there years ago, though) Small world!
For Paris wine stores, Aug gets my enthusiastic vote. It's kid-in-a-candy-shop kind of shopping for me.
Mark Lipton
originally posted by VLM:
Well, academic life has been pretty good to me. I didn't make as much during the bubble as my colleagues who went to Wall St., big Pharma and the like, but I am in no danger of losing my job and I get to work on things that may, if I'm lucky, has some benefit to humanity that isn't merely transient.
Word. Plus, the chicks are great.
Mark Lipton
originally posted by VLM:
Oh, and a pet peeveabout biology/immunology journals. I'm trying to replicate an analysis but there is not enough information in the paper nor the online supplement to do so. Pages and pages about staining this and titer that, blah, blah, blah. Don' these people realize the data is the science, not their little lab stuff, as cute as it is. More robust statistical analysis sections I say. Or at least give me a citation.
That's only the tip of the iceberg for that crowd. Heard of Photoshopped gels? Pfffttt. Slippery slope, my sweet ass.
Mark Lipton
Jeff Grossman
Jeff Grossman
A fluorescent raccoon? He really shouldn't mix his psychoactives like that.
Kevin: David Lillie is right, the wine shop directly across the street from the Pantheon is a cool place. (I found Lavinia cold and pricey. I hope to try Auge next time I'm there.)
Kevin: David Lillie is right, the wine shop directly across the street from the Pantheon is a cool place. (I found Lavinia cold and pricey. I hope to try Auge next time I'm there.)
Kevin Roberts
Kevin Roberts
originally posted by MLipton:
originally posted by Kevin Roberts:
I work for Integrated DNA, we sell DNA to the medical research market.
Funny, one of my first graduate students went to work there after getting his Ph. D. (in Organic Chemistry no less) with me. (He left there years ago, though) Small world!
For Paris wine stores, Aug gets my enthusiastic vote. It's kid-in-a-candy-shop kind of shopping for me.
Mark Lipton
Talk about a small world, I shared lab space/office with Mr. YY for years, we were in the same small group, for most of his time here. It was/is my job to scale up and do development work on things he invented. Every once in a while I'm reminded how stinking small the world is.
cheers,
Kevin
Auge is at the top of my shopping list!
originally posted by MLipton:
originally posted by VLM:
Well, academic life has been pretty good to me. I didn't make as much during the bubble as my colleagues who went to Wall St., big Pharma and the like, but I am in no danger of losing my job and I get to work on things that may, if I'm lucky, has some benefit to humanity that isn't merely transient.
Word. Plus, the chicks are great.
Mark Lipton
Yeah, but they don't let me near students anymore.
Ah, Carolina girls...
Kevin Roberts
Kevin Roberts
Thanks for the recommendations, I'll be sure to report back.
Cheers,
Kevin
Cheers,
Kevin
originally posted by Kevin Roberts:
Talk about a small world, I shared lab space/office with Mr. YY for years, we were in the same small group, for most of his time here. It was/is my job to scale up and do development work on things he invented. Every once in a while I'm reminded how stinking small the world is.
Yup, small indeed, Kevin. I hope that he at least stopped practicing saxophone at 2 am in the lab the way he used to here. Yong is a great guy, but a bit of a character, too. I'll drop your name the next time I exchange emails with him.
Mark Lipton