winereactionsarethenewtrend

originally posted by VLM:


Sorry, didn't mean to worry you. It was laparoscopic surgery with full anesthesia; hence, the intubation. Routine hernia surgery that had been delayed due to the pandemic. COVID-19 negative before and after. Hospitals, especially ones like Duke, are safer than grocery stores these days.

Yes, please hunker down. The midwest is a shitshow but vaccines are on the way (and isn't the mRNA platform just remarkable? I wish Joe were alive to see that).

It’s my choice for the next Medicine Nobel. And, yup, Joe would have been all over it. He’d probably have helped capitalize Moderna or the BioNTech couple. Thought of him the other night when we consumed our last Wind Gap Pinot (2013).

Mark Lipton
 
originally posted by MLipton:
originally posted by VLM:


Sorry, didn't mean to worry you. It was laparoscopic surgery with full anesthesia; hence, the intubation. Routine hernia surgery that had been delayed due to the pandemic. COVID-19 negative before and after. Hospitals, especially ones like Duke, are safer than grocery stores these days.

Yes, please hunker down. The midwest is a shitshow but vaccines are on the way (and isn't the mRNA platform just remarkable? I wish Joe were alive to see that).

It’s my choice for the next Medicine Nobel. And, yup, Joe would have been all over it. He’d probably have helped capitalize Moderna or the BioNTech couple. Thought of him the other night when we consumed our last Wind Gap Pinot (2013).

Mark Lipton

I was thinking about this and did a bit of cursory research trying to figure out who would get it, just by doing a half-assed (really quarter) lit dig. Honestly, it became a thing because Fauci was so frustrated that we were still making influenza vaccines in eggs that he and John Mascola and I think Barney Graham (probably a lot more players) held a summit and decided to push mRNA. The VRC has been a strong proponent ever since. I wish I had paid closer attention, but the guy we worked on an mRNA Zica vaccine with was an asshole so I tuned out a bit. It did work in monkeys though.

I like to imagine that Joe would have loved the elegance mixed with the practicality of the approach. Or maybe I'm just projecting.
 
originally posted by Rahsaan:
originally posted by VLM:

We opened up a 2015 Knoll Gruner Smaragd Schutt with Thanksgiving and it was loose and a bit warm. I could have handled it if it were rich (I had planned on that) but it didn't have the density I was hoping for. That being said, my taste was off from intubation during surgery on Tuesday and am now just getting back to normal taste-wise....

Glad that you are on the mend. Diminished faculties is always a tough thing.

And yes, I'm no expert in 2015 Wachau, but from the regions I know better it is not my favorite vintage expression, despite being able to find plenty of delicious wines.

while from kamptal rather than wachau, the 2015 gobelsburg riesling heiligenstein is fantastic. a wine that says, "i want to be your girlfriend", or words to that effect.
 
originally posted by Mark Anisman:
winereactionsarethenewtrend16 out this month

10 November : 2012 Schloss Gobelsburg Riesling Reserve Gaisberg
(...)paired with food.

Food is my favorite pairing with wine!
Thanks for the note on the Gobelsburg. I really should have more Gobelsburg in my cellar. Like their Grüner Veltliners as well.

12 November : 2001 Giacomo Conterno Barolo Cascina Francia
i have always thought most classically made Barolo benefits from being older than 20 years old (if not 25).

I think that's correct with some producer's such as Giacomo/Roberto Conterno or Bartolo Mascarello. But I would also consider Beppe Rinaldi or Giuseppe Mascarello classical producers and the Brunate/Le Coste '97 or Monprivato '89 were absolutely delicious with 7-8 years of age.
 
Since this vaccine works by introducing an mRNA sequence into our RNA to make it produce antibodies, does this not mean that all of us who receive such vaccines will henceforth be genetically modified organisms? Sign me up now. Of course, such vaccines are already in use for other diseases, such GMOa are already walking among us.
 
hi Anders,
I was specifically thinking of G Mascarello as I wrote that!
and i really think Gobelsburg's Michael Moosbrugger is a superstar and a tasting there a few years ago in 2012 was stunning. and he is a really humble, nice man to boot
M
 
originally posted by Jonathan Loesberg:
Since this vaccine works by introducing an mRNA sequence into our RNA to make it produce antibodies, does this not mean that all of us who receive such vaccines will henceforth be genetically modified organisms?

No. At least not how I understand the science. They basically trick our natural cells to create the non-disease but critical delivery portions of the virus, which our cells wouldn’t otherwise create, to trigger an immune response, and are GMOs themselves, but it’s not a gene therapy where your cellular DNA is altered. As far as I understand, they still don’t know how long the vaccine molecules stick around, which is one of the measures under study.
 
originally posted by Jayson Cohen:
originally posted by Jonathan Loesberg:
Since this vaccine works by introducing an mRNA sequence into our RNA to make it produce antibodies, does this not mean that all of us who receive such vaccines will henceforth be genetically modified organisms?

No. At least not how I understand the science. They basically trick our natural cells to create the non-disease but critical delivery portions of the virus, which our cells wouldn’t otherwise create, to trigger an immune response, and are GMOs themselves, but it’s not a gene therapy where your cellular DNA is altered. As far as I understand, they still don’t know how long the vaccine molecules stick around, which is one of the measures under study.

Nothing long-term altered here. The mRNA will disappear eventually. Which is why we need a second shot.
 
Injection of mRNA into your cells doesn’t result in a change to your genome. It’s the signal between DNA and protein and is degraded immediately after use.

Mark Lipton
 
All of you are putting a lot of pressure on the fact that the change is only temporary. You are, of course, right and thus we aren't permanently modified. But we are modified. Our cells themselves produce antibodies that they normally wouldn't. Would people who are against GMOs feel any better if all that rot resistant corn somehow lost its modification just prior to harvest?
 
originally posted by Jonathan Loesberg:
Would people who are against GMOs feel any better if all that rot resistant corn somehow lost its modification just prior to harvest?
It is not rot-resistant. It is herbicide-resistant and has had the insertion of Bacillus thuringiensis (Bt) genetic material so the plant is resistant to corn borer. And no, I would not feel any better because vast amounts of agricultural chemicals had polluted the environment.
 
originally posted by mark e:
originally posted by Jonathan Loesberg:
Would people who are against GMOs feel any better if all that rot resistant corn somehow lost its modification just prior to harvest?
It is not rot-resistant. It is herbicide-resistant and has had the insertion of Bacillus thuringiensis (Bt) genetic material so the plant is resistant to corn borer. And no, I would not feel any better because vast amounts of agricultural chemicals had polluted the environment.

One of the indications of GMO irrationality is how quickly the debate turns sideways. Chemical pollution is a real issue. It is also a different one. It has little to do with the kind of fears GMOs evoke of anti-natural entities.
 
originally posted by Jonathan Loesberg:
originally posted by mark e:
originally posted by Jonathan Loesberg:
Would people who are against GMOs feel any better if all that rot resistant corn somehow lost its modification just prior to harvest?
It is not rot-resistant. It is herbicide-resistant and has had the insertion of Bacillus thuringiensis (Bt) genetic material so the plant is resistant to corn borer. And no, I would not feel any better because vast amounts of agricultural chemicals had polluted the environment.

One of the indications of GMO irrationality is how quickly the debate turns sideways. Chemical pollution is a real issue. It is also a different one. It has little to do with the kind of fears GMOs evoke of anti-natural entities.

Accusations of irrationality don't help support your argument. My own issues with the use of GMOs are less the modification of the organisms themselves and much more (1) the environmental destruction they cause because of the cultivation practices in conventional farming (2) the irremediable pollution of other plant varieties' genetic material through pollination.
 
originally posted by mark e:
originally posted by Jonathan Loesberg:
originally posted by mark e:
originally posted by Jonathan Loesberg:
Would people who are against GMOs feel any better if all that rot resistant corn somehow lost its modification just prior to harvest?
It is not rot-resistant. It is herbicide-resistant and has had the insertion of Bacillus thuringiensis (Bt) genetic material so the plant is resistant to corn borer. And no, I would not feel any better because vast amounts of agricultural chemicals had polluted the environment.

One of the indications of GMO irrationality is how quickly the debate turns sideways. Chemical pollution is a real issue. It is also a different one. It has little to do with the kind of fears GMOs evoke of anti-natural entities.

Accusations of irrationality don't help support your argument. My own issues with the use of GMOs are less the modification of the organisms themselves and much more (1) the environmental destruction they cause because of the cultivation practices in conventional farming (2) the irremediable pollution of other plant varieties' genetic material through pollination.

How does planting a different variety of corn harm the practices of "conventinal" farming other than they are not planting a "conventional" variety?

With regard to your second point, I think the better argument is the attempt of agribusiness to protect copyright by banning the use by neighboring farmers of naturally cross-pollinated seeds. But that is not an issue of the GMOs themselves. It is an issue of agribusiness practices, which of course, affect far more than how they handle GMOs.

If, indeed, you are not against GMOs because of the inherent danger of producing "artificial" varieties though, but because of the consequences surrounding insufficient regulation, then, of course, I agree with you, but that's a different issue.
 
GMO means genetically modified. There is no genetic modification taking place during mRNA vaccination because no genes are modified.

Mark Lipton
 
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